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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FGFR3 All Species: 29.09
Human Site: S779 Identified Species: 58.18
UniProt: P22607 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P22607 NP_000133.1 806 87710 S779 P G G Q D T P S S S S S G D D
Chimpanzee Pan troglodytes XP_521622 819 91776 S786 P S Y P D T R S S C S S G D D
Rhesus Macaque Macaca mulatta XP_001101108 806 87642 S779 P G G Q D T P S S S S S G D D
Dog Lupus familis XP_545926 833 90729 S806 P G G Q D T P S S S S S G D D
Cat Felis silvestris
Mouse Mus musculus Q61851 801 87739 S774 P G G Q D T P S S S S S G D D
Rat Rattus norvegicus Q04589 822 91806 S785 P S F P D T R S S T C S S G E
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P18460 806 89712 S773 P A G Q D T H S T C S S G D D
Frog Xenopus laevis O42127 802 89497 S769 P P S Q D S H S T C S S G D D
Zebra Danio Brachydanio rerio Q9I8X3 800 89698 S767 P T C P D S N S T C S S G D D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q07407 729 82568 D700 Q T K E D Y L D V D I A N L D
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q10656 1040 118938 P959 E R S T A S G P V S P M E S F
Sea Urchin Strong. purpuratus Q26614 972 110463 R943 K T F Q E S E R M A F M G F R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 67.2 99.1 89.3 N.A. 92.4 62.9 N.A. N.A. 80.1 70.5 73.8 N.A. 37.5 N.A. 31.3 35.4
Protein Similarity: 100 77.5 99.2 91.9 N.A. 94.7 76.2 N.A. N.A. 87.5 79.4 82.3 N.A. 54 N.A. 46.6 50
P-Site Identity: 100 66.6 100 100 N.A. 100 40 N.A. N.A. 73.3 60 53.3 N.A. 13.3 N.A. 6.6 13.3
P-Site Similarity: 100 66.6 100 100 N.A. 100 53.3 N.A. N.A. 80 73.3 66.6 N.A. 26.6 N.A. 13.3 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 0 0 9 0 0 0 0 9 0 9 0 0 0 % A
% Cys: 0 0 9 0 0 0 0 0 0 34 9 0 0 0 0 % C
% Asp: 0 0 0 0 84 0 0 9 0 9 0 0 0 67 75 % D
% Glu: 9 0 0 9 9 0 9 0 0 0 0 0 9 0 9 % E
% Phe: 0 0 17 0 0 0 0 0 0 0 9 0 0 9 9 % F
% Gly: 0 34 42 0 0 0 9 0 0 0 0 0 75 9 0 % G
% His: 0 0 0 0 0 0 17 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % I
% Lys: 9 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 9 0 0 0 0 0 0 9 0 % L
% Met: 0 0 0 0 0 0 0 0 9 0 0 17 0 0 0 % M
% Asn: 0 0 0 0 0 0 9 0 0 0 0 0 9 0 0 % N
% Pro: 75 9 0 25 0 0 34 9 0 0 9 0 0 0 0 % P
% Gln: 9 0 0 59 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 9 0 0 0 0 17 9 0 0 0 0 0 0 9 % R
% Ser: 0 17 17 0 0 34 0 75 50 42 67 75 9 9 0 % S
% Thr: 0 25 0 9 0 59 0 0 25 9 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 17 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 9 0 0 9 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _